Colon Cancer Linked to Inherited Genes
Colon cancer is one of the most difficult and dangerous types of cancer that could affect a person. Like many other types of cancer, it requires early diagnosis in order to prevent serious damage in the future. One of the best ways to diagnose this type of cancer early, as doctors are beginning to discover, is by taking a look at an individual's family tree. Research shows that not only can early signs manifest as a way to tell if a person is going to develop colon cancer, but even before signs appear, doctors can take a look at an individual's hereditary traits to determine whether or not they may be at a larger risk.
Typically, colorectal cancer is classified as a hereditary or as an inherited illness when multiple generations of any family have a history of colorectal cancer. In such cases, several genetic mutations or general abnormalities appear, which can cause colorectal cancer. Not only does the mutation result in colorectal cancer, but it can also allow the cancer to become much more transmittable to the next generation of family members. Because a gene is a section of DNA that contains genetic code for producing bodily functions on a cellular level, the slightest variations can be enough to result in all types of issues, including the development of cancer.
Two of the most commonly inherited colorectal cancer syndromes include hereditary nonpolyposis colorectal cancer, which is abbreviated as HNPCC and familial adenomatous polyposis, which is abbreviated as FAP. These conditions can affect both women and men, and often the chance for children to inherit the disease can be relatively large as well, sometimes as high as a 50 percent chance of inheriting the gene. Studies show that the presence of these two cancer syndromes may account for less than five percent of all cases of colorectal cancers.
HNPCC is perhaps the most commonly inherited form of colon cancer. This syndrome accounts for approximately three percent of all documented types of colorectal cancer each year. People who have HNPCC will typically also have three or more family members and at least two generations of family who have had colorectal cancer in the past. The cancer often develops before the age of 50 as well. However, research shows that the presence of the syndrome is often not enough to guarantee the development of the cancer. Though not everyone who inherits the gene will develop the cancer, the risk is about 80 percent higher for these people. Additionally, individuals who have HNPCC may also be at a higher risk of inheriting or developing other cancers, including renal, uterine, stomach, pelvis and small intestine.
If you feel as though there are concerns regarding the state of your colorectal health, it is important for you to speak with the appropriate professionals as soon as possible. Contact your healthcare provider and schedule for a medical test at your earliest convenience. This is especially recommended for those who may believe that they are at a higher risk of developing these types of cancers, such as in those who have a family history of colorectal cancer. Through early detection, treatment options have a much higher chance to be significantly more successful, improving the rate at which you recover and go back to having a normal life.
